Nitrogen Substituted Phenothiazine Derivatives: Modelling of Molecular Self-Assembling

Molecular modeling of the weakly bounded dimers of some phenothiazine derivatives

The intermolecular π-π stacking interaction between some phenothiazine derivatives has been investigated using the Hartree-Fock (HF) and the local second order Møller-Plesset perturbation theory (LMP2) methods. Two different conformations (parallel and antiparallel stacking) of ethyl-phenothiazine and the parallel stacking of thio-methyl-phenothiazine were investigated. In all three cases the H...

Microwave Assisted Synthesis, Characterization and Antimicrobial Activity of 10H-Phenothiazine Derivatives

A new environmental benign method for synthesis of phenothiazine derivatives using microwave irradiation has reported. A mixture of o-substituted aromatic amine and p-substituted phenol converted into biphenyl amine derivative using microwave irradiation. Further, thionation of biphenyl amines under same irradiation has provided the title phenothiazine derivatives. The later compounds then oxid...

Synthesis of Phenothiazine Substituted Schiff Derivatives and their in vitro antibacterial and antioxidant Studies

Synthesis of Some Nitrogen Functional Derivatives of 5-substituted-6-azauracil as Biologically Active Compounds

3-Arylhydrazono-2,4-dioxo-4-phenylbutanoates have been prepared by the coupling of benzoylpyruvate with aryldiazonium chlorides. Reactions of the 3-arylhydrazono-2,4- dioxo-4-phenylbutanoates with 1-aminoguanidine, semicarbazide, and thiosemicarbazide gave 5-substituted 2-imino-6-azauracil (3a), 6-azauracil (3b), and 2-thio-6-azauracil (3c), respectively. The analytical data of these compounds ...

Synthesis of Nitrogen Functional Derivatives of 5-substituted-6-azauracil as one of the Four Nucleobases in the Nucleic Acid of RNA

3-Arylhydrazono-2,4-dioxo-4-phenylbutanoateshave been prepared by the coupling of benzoylpyruvate with aryldiazonium chlorides.Reactions ofthe 3-arylhydrazono-2,4-dioxo-4-phenylbutanoateswith 1-aminoguanidine, semicarbazide, and thiosemicarbazidegave5-substituted 2-imino-6-azauracil (3a),6-azauracil (3b), and 2-thio-6-azauracil (3c), respectively. The analytical data of these compounds - IR, 1H...